Among 3,728 primary hyperparathyroidism patients, those undergoing parathyroidectomy had reduced risks of new-onset cognitive impairment (HR: 0.65), somnolence (HR: 0.45), and schizophrenia (HR: 0.08) compared to nonoperative management. No significant risk reduction was observed for anxiety, depression, or suicidal ideation. Additionally, surgical patients were less likely to require inpatient care for neuropsychiatric disorders (0.3% vs. 1.8%, p<0.001). These findings suggest the potential neuropsychiatric benefits of parathyroidectomy in managing primary hyperparathyroidism.
• Why it matters: Neuropsychiatric disorders frequently manifest in primary hyperparathyroidism.
Journal Article by Song Z, Balachandra S (…) Chen H et 6 al. in World J Surg
© 2024 The Author(s). World Journal of Surgery published by John Wiley & Sons Ltd on behalf of International Society of Surgery/Société Internationale de Chirurgie (ISS/SIC).