A retrospective analysis involving 645 patients with cT2 staged adenocarcinomas indicated that neoadjuvant treatment followed by surgery (nat/s) yields significantly better overall survival compared to primary surgery (ps). Median overall survival was 114.0 months for nat/s versus 51.0 months for ps in the cT2cnany cohort. Additionally, nat/s was associated with improved disease-free survival in cT2cn0 patients. Notably, 38.1% of cT2cnany and 34.2% of cT2cn0 patients were found to be understaged.
Journal Article by Wirsik NM, Kooij CD (…) Bruns CJ et 23 al. in Ann Surg
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