A multicenter study analyzed 535 patients with single large hepatocellular carcinoma (slhcc). Results indicated that major hepatectomy led to significantly higher major complications and no long-term survival benefits compared to minor resections, especially left lateral sectionectomy, which was associated with better overall survival (p=0.02). The absence of oncological benefits from major resection suggests minor resections should be favored when feasible and oncologically appropriate, promoting improved surgical outcomes for slhcc patients.
Multicenter Study by Garancini M, Serenari M (…) Romano F et 49 al. in Langenbecks Arch Surg
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