Laparoscopic repair reduces mortality for peptic ulcer perforation

In a systematic review of nine randomized controlled trials involving 670 patients, laparoscopic repair for peptic ulcer perforation (PUP) demonstrated significantly lower mortality rates (risk ratio 0.37) and morbidity, alongside a reduced length of hospital stay compared to open surgery. The findings suggest that laparoscopic repair is preferable for PUP treatment, contingent upon available surgical expertise. Overall, this study advocates for a shift towards laparoscopic methods in managing PUP cases effectively.