A new predictive model, combining small ribonucleic acids (srnas) and clinical factors, shows promise in forecasting pathologic complete response (pcr) in esophageal squamous cell carcinoma post-neoadjuvant chemoradiotherapy. Among 99 patients, significant predictors included isomirs of let-7b and mir-93, plus specific clinical indicators. The model achieved an area under the curve of 0.84, suggesting its potential utility in enhancing treatment decision-making for patients undergoing surgery after chemoradiation.
Journal Article by Hirohata R, Yamamoto Y (…) Tahara H et 5 al. in Ann Surg Oncol
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