Integrating Lipid and Inflammation Scores Enhances Gastric Cancer Prognosis

Incorporating the Circulating Lipid and Inflammation Risk Score (CLIRS) significantly predicts long-term survival in gastric cancer patients. Analysis of 2,534 patients revealed that CLIRS is an independent prognostic factor for overall (HR 1.529) and disease-free survival (HR 1.511). Nomograms based on CLIRS outperformed traditional pTNM staging in forecasting postoperative outcomes, highlighting that high-risk patients face earlier and more sustained recurrences. This study offers a promising tool for improving clinical decision-making in gastric cancer management.