Lymph node size on preoperative CT predicts colon cancer metastasis.
Measuring lymph node size via preoperative CT significantly predicts pathological lymph node metastasis in colon cancer. Researchers established optimal cutoff values of 6.5 mm for maximum long diameter and 5.5 mm for short diameter, with AUCs of 0.7794 and 0.7755, respectively. Importantly, cutoff values varied by tumor location—higher in the right-sided colon (7.7 mm and 5.9 mm) than in the left (5.8 mm and 5.2 mm)—suggesting tailored diagnostic approaches are necessary.
Removing the rectal tumor and liver spread in one operation did not clearly raise complications or hurt survival compared with two separate operations, a French national study found.
A Japanese randomized trial found that a 14-day schedule of trifluridine-tipiracil plus bevacizumab keeps patients with metastatic colorectal cancer alive as long as the standard 28-day schedule, with far less toxicity.
