Advances in cell-free DNA (cfDNA) research highlight its utility as a non-invasive method for screening advanced colorectal adenoma, which is crucial for preventing colorectal carcinoma. The study explores cfDNA’s unique characteristics, such as molecule size, methylation patterns, and integrity, promising enhanced detection rates. This emerging liquid biopsy technique could offer a vital alternative to painful colonoscopy procedures, potentially increasing early-stage colorectal cancer diagnostic opportunities. Continued development in this area could significantly reduce associated morbidity rates.
Review by Chen BH, Ng HI (…) Wang GQ et 2 al. in Eur J Med Res
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