Higher stages of the OLGA and OLGIM staging systems significantly correlate with an elevated risk of developing high-grade dysplasia (HGD) and gastric cancer (GC). A systematic review and meta-analysis of eight prospective cohort studies found that moving from OLGA/OLGIM categories 0-II to III-IV notably increases the likelihood of these outcomes. This validates the use of these classification systems in evaluating gastric cancer risk and supports their role in developing endoscopic surveillance programs.
© The Author(s), 2025.