A study involving 165 patients diagnosed with hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) identified alpha-fetoprotein (AFP) and carbohydrate antigen 19-9 (CA19-9) as key tumor markers for accurate preoperative differentiation. Elevated white blood cell counts, neutrophil-to-lymphocyte ratios, and monocyte counts were linked to increased ICC risk, while higher lymphocyte-to-monocyte ratios indicated protection. The predictive model achieved an area under the curve of 0.791, improving diagnostic strategies for personalized treatment in primary liver cancer.
Journal Article by Shi W, Jin W (…) Hu S et 2 al. in Medicine (Baltimore)
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