A systematic review and meta-analysis reveals that contact X-ray brachytherapy (CXB) provides an 82% clinical complete response rate in rectal cancer patients, presenting a compelling alternative to radical surgery. With a 14% salvage surgery rate and 81% organ preservation, CXB demonstrates long-term disease control, particularly beneficial for stoma-averse and older patients. The findings suggest clinicians should incorporate CXB into discussions about treatment options for rectal cancer, highlighting its safety and effectiveness.
Review by Powell SG, Wyatt JNR (…) Myint AS et 11 al. in Eur J Surg Oncol
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