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Upper Gastrointestinal Tract ·

Optimal lymph node yield determined for accurate gastric cancer staging

A cohort study of 6,463 gastric cancer patients established new benchmarks for lymph node harvesting in gastrectomy. Results showed that just five lymph nodes (LNs) sufficed for CT1 patients to maintain a low risk of false negatives, while CT2 patients required 17 nodes. For CT3 and CT4 patients, even 35 nodes did not significantly reduce risks. Depending on surgical type, guidelines emerged: 25 nodes for subtotal gastrectomy and 59 for total gastrectomy to achieve 90% confidence in ruling out nodal disease.

Journal Article by Li R, Sun X (…) Liu N et 4 al. in World J Surg Oncol

© 2025. The Author(s).

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