Sequential injection-electrocoagulation improves hemostasis in ESD.

A randomized controlled trial involving 69 patients demonstrated that the sequential injection-electrocoagulation method significantly reduced the median time to hemostasis during endoscopic submucosal dissection (17 seconds) compared to traditional electrocoagulation (22 seconds), with p < 0.001. The experimental method also yielded higher visibility scores (3.24 vs. 2.82; p < 0.001) and reduced muscle injuries compared to the control group. Notably, one case of perforation was recorded in the control group, highlighting increased risks with traditional methods.