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Upper Gastrointestinal Tract ·

High Postoperative IL-6 Levels Deteriorate Outcomes in Esophageal Cancer

Elevated serum interleukin-6 (IL-6) levels one day post-minimally invasive esophagectomy (MIE) correlate with significantly poorer overall survival rates and nutritional status in esophageal cancer patients. In a cohort of 336 patients, those with IL-6 levels ≥60 pg/ml exhibited a 2-year overall survival rate of 69.8%, compared to 80.6% for those with lower levels. The study underscores the necessity of targeting IL-6 in perioperative care to potentially enhance patient outcomes after surgery.

Journal Article by Kubo Y, Fujita T (…) Daiko H et 3 al. in Ann Surg Oncol

© 2025. Society of Surgical Oncology.

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