A retrospective study involving 1,884 patients revealed a 12.3% incidence of sepsis post-major abdominal surgery. Elevated triglyceride-glucose index (TyGI) levels were associated with a 90.7% increased risk of sepsis, as indicated by a hazard ratio of 1.907. Subgroup analysis identified significant interaction effects, particularly in patients with low HDL cholesterol. Incorporating TyGI into clinical prediction models improved accuracy, enhancing the c-statistic from 0.696 to 0.722, indicating its potential value in identifying high-risk patients.
Journal Article by Xia Q, Wang Y, Wu D and Lv Z in Pak J Med Sci
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