Omitting abdominal drainage after left pancreatectomy lowers complications

The PANDRA II trial revealed that patients undergoing left pancreatectomy without routine abdominal drainage had similar morbidity rates compared to those with drainage. The no-drain group demonstrated noninferiority in overall postoperative morbidity, with a comprehensive complication index of 13.90 versus 19.43 for the drain group (p < 0.001). Additionally, the no-drain approach resulted in a significant reduction in overall complication rates (50.41% vs 78.40%, p < 0.001). Specific complications remained comparable.