A novel minimal important difference (MID) for the Comprehensive Complication Index (CCI) offers clarity on surgical outcomes for major abdominal surgery patients. Analyzing data from 1,583 patients across four studies, findings reveal an MID of 12 points in the CCI crucial for interpreting clinical significance and guiding sample size calculations in future research. This metric emphasizes patient-centered outcomes, bridging gaps between statistical significance and meaningful clinical changes.
Journal Article by Abbassi F, Pfister M (…) Clavien PA et 18 al. in Ann Surg
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