Gut microbiota alterations post-gastrectomy are linked to inflammation and complication risks. A systematic review of 13 studies encompassing 937 patients revealed reduced microbial diversity after surgery, correlating with negative surgical outcomes. Notably, oral probiotics demonstrated efficacy in restoring microbiota diversity and decreasing postoperative complications. However, consensus on which specific probiotics to use remains elusive. Focus needs to shift towards targeted interventions to optimize perioperative management for gastric cancer patients.
Review by Tang X, Wang X (…) Fan Y et 4 al. in Eur J Surg Oncol
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