Patients with very early intrahepatic cholangiocarcinoma (ICC) show significant long-term survival, with 1-, 3-, and 5-year overall survival rates at 92.3%, 72.6%, and 58.0%, respectively. However, elevated carbohydrate antigen 19-9 (CA19-9) levels correlate with worse overall and recurrence-free survival rates, indicating more aggressive tumor features. Such biomarkers could refine perioperative treatment strategies and identify patients at risk for metastatic disease and vascular invasions, enhancing clinical decision-making following liver resection.
Journal Article by Endo Y, Kawashima J (…) Pawlik TM et 17 al. in J Surg Oncol
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