Removing 19 or More Negative Lymph Nodes Enhances Survival in Esophageal Cancer

A systematic review reveals that removing 19 or more negative lymph nodes (NLNs) during esophageal cancer surgery correlates with significantly improved survival rates, particularly in adenocarcinoma patients. Specifically, the hazard ratio indicates a 12% improved survival compared to those with fewer than 19 NLNs removed. This finding underscores the importance of surgical strategy, suggesting that surgical guidelines should now include this NLN removal threshold for better patient outcomes.

Meta-Analysis by Bahardoust M, Torabi S (…) Tizmaghz A et 6 al. in BMC Surg

© 2025. The Author(s).

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