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Impact of Preoperative Opioid Use Disorder Meds on Surgery Outcomes

Preoperative medication for opioid use disorder (OUD) reduces complications in surgical patients with OUD.

  • Among 917,754 surgical patients, 1.6% had OUD; of these, 27.6% were using medication for OUD preoperatively.
  • Patients with OUD had significantly higher rates of postoperative opioid use (42.2% vs. 8.2%), ED visits (21.7% vs. 6.9%), and readmissions (6.6% vs. 2.2%) compared to opioid-naïve patients.

Preoperative use of medications like buprenorphine or methadone can lead to fewer complications and should be considered in surgical planning for this patient group.

Journal Article by Li AH, Huang Y (…) Wright JD et 5 al. in Ann Surg Open

Copyright © 2025 The Author(s). Published by Wolters Kluwer Health, Inc.

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