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Innovative Two-Stage Hepatectomy for Intrahepatic Cholangiocarcinoma

Surgeons can safely resect complex liver tumors using a novel two-stage approach that minimizes ischemic injury.

  • Combining total vascular exclusion with veno-venous ECMO and hypothermic perfusion led to negative margins in a patient with unresectable intrahepatic cholangiocarcinoma.
  • Operative time was 4 hours and 3 minutes, with 72 minutes of hypothermic perfusion and 130 minutes of ECMO support, resulting in uneventful recovery.

Consider this approach for patients with centrally located liver tumors previously deemed unresectable.

  • The method may reduce complications and improve outcomes in high-risk surgical cases.

Journal Article by van Beekum CJ, Felgendreff P (…) Schmelzle M et 10 al. in Ann Surg Oncol

© 2025. The Author(s).

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