Extended Cholecystectomy Reduces Cancer Death in Stage I Gallbladder Cancer

Extended cholecystectomy offers better survival for stage I gallbladder cancer patients over simple cholecystectomy.

• 1-year cancer-specific death rates: 6.43% (EC) vs. 11.5% (SC)
• 5-year cancer-specific death rates: 15.3% (EC) vs. 28.9% (SC), p=0.002

For T1b disease, extended cholecystectomy is advisable, while simple cholecystectomy may suffice for T1a.

• Robust survival prediction tools can help tailor patient management based on tumor characteristics.