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PAXG Outperforms mFOLFIRINOX in Resectable Pancreatic Cancer

PAXG shows superior efficacy over mFOLFIRINOX for patients with resectable pancreatic ductal adenocarcinoma.

  • Median event-free survival (EFS) for PAXG is 16.0 months compared to 10.2 months for mFOLFIRINOX.
  • EFS hazard ratio is 0.63, indicating a significant benefit for PAXG (p=0.0018).

Surgeons should consider PAXG as the preferred preoperative chemotherapy regimen for this patient population.

  • Adverse events were similar between both groups, suggesting PAXG’s safety profile remains acceptable.

Journal Article by Reni M, Macchini M (…) Falconi M et 22 al. in Lancet

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