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Impact of Tumor Progression on Hepatectomy Outcomes in NETLM

Preoperative tumor progression significantly predicts early mortality in patients undergoing cytoreductive hepatectomy for neuroendocrine tumor liver metastases.

  • 47% of short-term survivors had preoperative progression compared to 16.6% of long-term survivors (p < 0.001).
  • Patients with pancreatic neuroendocrine tumors and progression faced a median overall survival of just 1.8 years (p = 0.042).

Incorporating tumor progression metrics into preoperative evaluations can refine surgical decision-making and improve patient outcomes.

  • Tumor growth over 20% and weekly growth over 1.04% were strongly linked to early mortality (p < 0.001).

Journal Article by Podrascanin V, Ammann M (…) Starlinger PP et 10 al. in Eur J Surg Oncol

Copyright © 2025 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.

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