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Perspectives, Opinions and Curiosities ·

Postoperative Ketamine Infusion Cuts Pain and Opioid Use

Postoperative ketamine infusion within ERAS protocols significantly improves pain management and reduces opioid consumption following elective open abdominal surgeries.

  • Pain scores decreased by 0.53 on the VAS scale within the first 24 hours (p < 0.05).
  • Opioid use dropped by 0.44 morphine equivalents during the same period (p < 0.05).

While ketamine had no significant effects on postoperative nausea and vomiting or other adverse events, it shows promise as an effective pain management tool.

  • Further research is needed to determine optimal dosing and administration strategies for best outcomes.

Systematic Review by Molla YD, Setargew KH and Alemu HT in BMC Surg

© 2025. The Author(s).

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