A 4-day course of sulbactam/ampicillin effectively lowers perineal wound infections after abdominoperineal resection for rectal cancer.
- Incidence of perineal wound infection dropped significantly from 46% with cefmetazole to 14% with sulbactam/ampicillin.
- This multicenter trial involved 80 patients, with a focus on surgical site infections and overall complications.
Consider shifting to a 4-day sulbactam/ampicillin regimen to reduce infection rates and enhance patient outcomes post-surgery.
Journal Article by Nankaku A, Kasai S (…) Kinugasa Y et 10 al. in Ann Gastroenterol Surg
© 2025 The Author(s). Annals of Gastroenterological Surgery published by John Wiley & Sons Australia, Ltd on behalf of The Japanese Society of Gastroenterological Surgery.