Active surveillance after neoadjuvant chemoradiotherapy provides similar survival to surgery while significantly enhancing quality of life for patients with locally advanced oesophageal cancer.
- Active surveillance patients reported significantly better scores for dysphagia, dyspnoea, fatigue, and physical functioning at 6 months (Cohen’s d of -1.09, -0.63, -0.70, and 0.77, all p ≤ 0.001).
- Dysphagia improvements were sustained at 2 years (Cohen’s d of -0.79, p < 0.001).
Consider active surveillance as a viable management strategy for eligible patients, balancing safety and quality of life.
Multicenter Study by Gangaram Panday SSG, van der Wilk BJ (…) Wijnhoven BPL et 34 al. in Br J Surg
© The Author(s) 2026. Published by Oxford University Press on behalf of BJS Foundation Ltd. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.
© The Author(s) 2026. Published by Oxford University Press on behalf of BJS Foundation Ltd. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.