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EUS-Guided Biopsy for Pancreatic Cysts: Key Outcomes and Risks

EUS-guided through-the-needle biopsy (EUS-TTNB) offers valuable diagnostic insights for pancreatic cysts but carries significant risks that surgeons must navigate.

  • Diagnostic adequacy is high at 80.3%, with changes in management seen in 16.3% of cases.
  • Adverse events (AEs) occurred in 20.9% of procedures, predominantly acute pancreatitis (15%).
  • Intraductal papillary mucinous neoplasm (IPMN) significantly raises AE risk (OR 2.24).

Surgeons should use a risk stratification model to enhance patient selection and mitigate complications.

  • Risk categories: low (11.9% AE), moderate (20.6% AE), high (37.0% AE for patients with IPMN).

Journal Article by Lee HS, Song TJ (…) Seo DW et 3 al. in Gastrointest Endosc

Copyright © 2026 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.

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