ISGPS Class D Increases Pancreatic Fistula Risk After Surgery

A new classification system helps predict pancreatic fistula risk after pancreatoduodenectomy.

Overall postoperative pancreatic fistula (POPF) rate is 19.9%.
Class D patients have a 37.4% POPF rate, significantly higher than Class A’s 9.0% (p < 0.001).

Surgical decision-making should incorporate this classification for better patient selection.

Class D patients show a 6-fold increased risk of POPF compared to Class A.

Multicenter Study by Schuh F, Yildirim B (…) Probst P et 12 al. in Ann Surg

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