Deceased donor liver transplantation (DDLT) improves survival for patients with unresectable colorectal liver metastases (CLM).
- Overall survival is impressive at 96.9% at one year and 84.8% at two years.
- Disease-free survival at one year is 62.7%; however, recurrence occurs in 42.9% of cases.
Accurate patient selection is crucial; KRAS mutation significantly links to recurrence (p=0.01).
- HAIP therapy showed no survival advantage, indicating a need for larger studies to verify its impact.
Journal Article by Hill AL, Cullinan DR (…) Doyle MB et 7 al. in J Am Coll Surg
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