Liver Transplant Offers Hope for Colorectal Liver Metastases

Deceased donor liver transplantation (DDLT) improves survival for patients with unresectable colorectal liver metastases (CLM).

• Overall survival is impressive at 96.9% at one year and 84.8% at two years.
• Disease-free survival at one year is 62.7%; however, recurrence occurs in 42.9% of cases.

Accurate patient selection is crucial; KRAS mutation significantly links to recurrence (p=0.01).

• HAIP therapy showed no survival advantage, indicating a need for larger studies to verify its impact.