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Socioeconomic Disadvantage Cuts Survival in Pancreatic Cancer

Living in socioeconomically disadvantaged areas significantly reduces survival in patients with nonmetastatic pancreatic cancer, even with guideline-concordant treatment.

  • Patients in high deprivation areas had a 1.9 times higher risk of decreased survival compared to those in lower deprivation areas.
  • Not receiving guideline-concordant treatment increased the risk of poor outcomes by 1.7 times.

Surgeons should consider the socioeconomic context when selecting patients for treatment and address barriers to care.

  • Factors like aggressive tumor biology and high comorbidity also contribute to worse survival outcomes.

Multicenter Study by Fonseca AL, Liapis I (…) Heslin MJ et 7 al. in J Am Coll Surg

Copyright © 2026 by the American College of Surgeons. Published by Wolters Kluwer Health, Inc. All rights reserved.

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