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Perspectives, Opinions and Curiosities ·

Tranexamic Acid Cuts Blood Loss in Cancer Surgeries

Tranexamic acid significantly reduces blood loss and transfusion needs during cancer surgeries, which can improve patient outcomes.

  • In 16 trials with 1,830 patients, TXA cut total, intraoperative, and postoperative blood loss compared to control.
  • It lowered intraoperative blood component need and perioperative red blood cell transfusions.

TXA may also modestly reduce operative time without increasing complications or mortality.

  • Certainty of evidence varied, with many outcomes rated moderate or low quality.

Review by Soliman A, Azim AAA (…) Qutob IA et 6 al. in Ann Surg Oncol

© 2026. Society of Surgical Oncology.

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