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Predicting Post-hepatectomy Liver Failure in HCC Patients

Understanding risk factors can guide surgical decisions for patients with hepatocellular carcinoma.

  • Post-hepatectomy liver failure (PHLF) occurred in 7% of patients, linked to a 30.8% major complication rate and 9.2% 90-day mortality.
  • PHLF patients had 5-year survival of 52.8%, compared to 78.8% in non-PHLF patients.

Identifying independent risk factors such as hepatitis B status and indocyanine green retention supports tailored surgical planning.

  • A predictive nomogram demonstrated strong performance (AUC 0.771), allowing for better preoperative risk assessment.

Journal Article by Jo HS, Kim NR (…) Kim DS et 2 al. in Ann Surg Oncol

© 2026. Society of Surgical Oncology.

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