Surgical management of gastro-entero-pancreatic neuroendocrine tumors is inconsistent, highlighting the need for clearer guidelines.
- Only 4% of studies on surgery for GEP-NETs are prospective; 96.7% are retrospective.
- Most research focuses on small pancreatic NETs and liver metastases, limiting broader applicability.
Surgeons should prioritize evidence from multi-institutional studies for better patient selection and outcomes.
- Current literature primarily involves single-center analyses, diminishing evidence reliability.
Review by Meloche-Dumas L, Bleicher J (…) Hallet J et 6 al. in Ann Surg Oncol
© 2026. Society of Surgical Oncology.