Mesh implantation during hernia repairs does not increase the risk of developing autoimmune diseases compared to surgeries without mesh.

• Incidence of new autoimmune disease was 1.1% for hernia patients and 1.5% for cholecystectomy controls, showing no statistically significant difference (p = 0.520).
• This finding challenges fears surrounding mesh use, which may influence patient decision-making and reduce legal claims.

This research supports the continued use of polypropylene mesh in hernia repairs, reassuring both surgeons and patients.