High-volume hospitals improve survival and reduce costs for necrotizing pancreatitis patients.

• Patients at high-volume centers had lower odds of mortality (odds ratio: 0.78) compared to low-volume hospitals.
• Even with higher overall mortality rates, high-volume hospitals had lower mortality for intervention-only patients (7.5% vs 12.0%, p < 0.001).
• High-volume centers also associated with shorter hospital stays and lower healthcare costs.

Consider directing patients to high-volume centers for better outcomes and resource management.