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Perspectives, Opinions and Curiosities ·

Prehabilitation Shows Promise in Abdominal Cancer Surgery

Multimodal prehabilitation may enhance baseline immune function in patients before abdominal cancer surgery, but its effect on postoperative immune outcomes appears limited.

  • In a study of 130 patients (102 prehabilitation, 28 control), prehabilitation reduced pro-inflammatory cytokines and increased IL-10 levels.
  • No significant immune function differences were noted on postoperative day 1 between groups.

This suggests prehabilitation might optimize pre-surgical readiness, but benefits for postoperative immune response may not be substantial.

Journal Article by Jacobs LMC, Drager LD (…) Warlé MC et 6 al. in Br J Surg

© The Author(s) 2026. Published by Oxford University Press on behalf of BJS Foundation Ltd.

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