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Local Therapies Improve Survival in Recurrent Pancreatic Cancer

Surgeons should consider local therapies for recurrent pancreatic ductal adenocarcinoma as they show significant survival benefits.

  • For liver-only recurrence, local therapy leads to longer survival than chemotherapy alone (HR 0.26).
  • Surgical resection for lung-only recurrence offers better survival compared to conventional treatment (HR 0.35).

Careful patient selection and tailored approaches could enhance outcomes in recurrence management.

  • Locoregional resection also correlates with increased survival (HR 0.52).

Journal Article by Maekawa A, Perri G (…) Marchegiani G et 6 al. in Ann Surg Oncol

© 2026. The Author(s).

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