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Understanding Recurrence Patterns in Intrahepatic Cholangiocarcinoma

Post-surgery tumor features impact recurrence patterns in intrahepatic cholangiocarcinoma, affecting long-term outcomes and follow-up strategies.

  • Among 1,328 patients, 57.5% experienced recurrence; 23% had both intra- and extrahepatic recurrence.
  • Three or more metastatic lymph nodes increased the chance of combined recurrence (adjusted odds ratio 3.47).
  • Patients with combined recurrence had worse survival outcomes (hazard ratio 1.63) and lower likelihood of receiving further curative treatment (odds ratio 0.14).

Assessing these tumor features may refine postoperative surveillance and patient management strategies.

Journal Article by Yuza K, Chatzipanagiotou OP (…) Pawlik TM et 16 al. in Br J Surg

© The Author(s) 2026. Published by Oxford University Press on behalf of BJS Foundation Ltd. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.
© The Author(s) 2026. Published by Oxford University Press on behalf of BJS Foundation Ltd. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.

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