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Perspectives, Opinions and Curiosities ·

Gut Microbiome Impacts Surgical Outcomes and Cancer Treatment

Understanding the gut microbiome can enhance surgical outcomes and long-term cancer patient care.

  • Perioperative synbiotics reduce infectious complications by 45% in colorectal surgery and 64% in major liver surgery.
  • Preoperative oral care cuts post-esophagectomy pneumonia risk by 50%.

Targeted microbiome interventions are essential for optimizing surgical recovery and minimizing complications.

  • Antibiotic exposure prior to melanoma treatment may reduce immunotherapy effectiveness, but fecal microbiota transplantation can improve response rates by up to 80%.

Journal Article by Dang J, Lee Y (…) Mocanu V et 3 al. in Br J Surg

© The Author(s) 2026. Published by Oxford University Press on behalf of BJS Foundation Ltd. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.

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