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Hepatocellular Carcinoma Outcomes Differ Markedly by Region

A study comparing hepatocellular carcinoma (HCC) patients in South Africa and Sweden found stark differences in survival and access to curative treatment, underscoring the need for region-specific guidelines.

  • South African HCC patients were younger (median age 50 vs. 71) and predominantly had hepatitis B-related HCC (60% vs. 3.6%) compared to their Swedish counterparts.
  • Only 9.2% of South African patients received curative therapies, versus 42.5% in Sweden, resulting in significantly worse overall survival rates: 1-year survival was 17.8% in South Africa vs. 59.3% in Sweden.

These disparities highlight the urgency for tailored clinical guidelines to improve HCC management in lower-income settings.

Comparative Study by Sobnach S, Bayadsi H (…) Jonas E et 10 al. in Br J Surg

© The Author(s) 2026. Published by Oxford University Press on behalf of BJS Foundation Ltd.

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