Author: STITCHES Newsletter

Minimally Invasive Esophagectomy Beats Open Surgery in Older Patients

Minimally invasive esophagectomy (MIE) significantly improves survival for older esophageal cancer patients compared to open esophagectomy (OE). MIE offers a median overall survival of 60.17 months vs. 29.18 months for OE (HR=1.566, p=0.002). Disease-free survival is also better with MIE (37.70 months vs. 25.20 months, HR=1.411, p=0.010). MIE has similar major complication rates as OE, […]

Predicting Bowel Resection Risk in Incarcerated Hernias

This study identifies key predictors for bowel resection in incarcerated abdominal wall hernias, which has crucial implications for surgical decision-making. 12% of patients needed bowel resection due to strangulation. Elevated white blood cell count, C-reactive protein, and lactate levels linked to a higher risk of resection. Bowel obstruction and femoral hernia also significantly increase risk […]

Rethinking Surgical Trials in Esophagogastric Cancer

Multicenter trials in esophagogastric cancer have not improved overall survival, raising urgent questions about trial design. 27 trials were analyzed; only 10 aimed for survival superiority, none achieved significant benefits. Common issues included limited surgeon credentialing and poor adherence monitoring. Trials often lacked adequate power and internal piloting, with a 10% nonadherence potentially halving statistical […]

Low Ligation of IMA Enhances Survival in Rectosigmoid Surgery

Low ligation of the inferior mesenteric artery improves outcomes for rectal and sigmoid cancer patients. Low ligation significantly boosts 5-year overall survival (HR 0.69, p = 0.026). It reduces anastomotic leak rates (OR 0.71, p = 0.050) without affecting disease-free survival or lymph node yield. No increase in overall complications, operative time, or blood loss […]

Endoscopic Ultrasound Outperforms PTBD for Biliary Obstruction

Endoscopic ultrasound (EUS) is a cost-effective strategy for managing malignant distal biliary obstruction (MDBO) after failed ERCP, leading to better outcomes. EUS-guided biliary drainage (EUS-GB) cost $14,520, yielding 0.38 QALYs and an incremental net monetary benefit (NMB) of $37,768. EUS-guided choledochoduodenostomy (EUS-CBD) cost $17,694, providing 0.55 QALYs and an incremental NMB of $52,171. EUS techniques […]

Innovative ultrasound technique enhances liver surgery outcomes

A novel ultrasound-guided technique to compress the middle hepatic vein allows for better detection of left-sided communicating veins, improving surgical options. Left-sided communicating veins were detected in 71% of patients using this method. Surgical strategies were modified in 57% of patients, enabling more parenchyma-sparing resections. This technique could expand the criteria for liver resections and […]

Transcutaneous Ultrasound Offers Hope for Vocal Cord Paralysis Diagnosis

Transcutaneous laryngeal ultrasound shows promise in detecting vocal cord paralysis after esophagectomy, crucial for surgical outcomes. Pooled sensitivity of 79% and specificity of 95% highlight its potential as a diagnostic tool. Vocal cord visualization achieved rates of 92.3%, with a 29% incidence of vocal cord paralysis post-surgery. Consider this tool for assessing high-risk patients, but […]

Guidelines Improve Barrett’s Esophagus Surveillance

Surgeons should know that new guidelines clarify endoscopic surveillance for Barrett’s esophagus (BE) to reduce the risk of esophageal adenocarcinoma. A conditional recommendation supports surveillance for patients with nondysplastic BE. Strong recommendation for high-definition white light endoscopy combined with chromoendoscopy over white light alone. No specific endorsement for enhanced sampling techniques or biomarkers to predict […]

Alcohol Withdrawal Syndrome Complicates Surgery Outcomes

Patients undergoing major surgery with alcohol withdrawal syndrome (AWS) face worse outcomes and higher costs. AWS affected 0.5% of 3 million surgical patients, increasing complications by 37% and respiratory failure risk by 144%. Length of stay was significantly longer at 11 days versus 6 days, with hospitalization costs surging by $10,030 per patient. AWS screening […]

Surgery Alone Improves Outcomes in Resectable Pancreatic Cancer

Surgical resection without multimodal treatment for early-stage pancreatic cancer can lead to better survival outcomes. Upfront surgery showed a median overall survival of 14.09 months compared to 6.34 months for those who refused surgery. One-year survival rates were 56% with surgery versus 26% without. R0 resection patients had a median survival of 17.87 months, significantly […]