After a decade of follow-up in the SM-BOSS trial, Roux-en-Y gastric bypass (RYGB) demonstrated superior efficacy in achieving percentage excess body mass index loss compared to sleeve gastrectomy (SG), with means of 65.9% and 56.1% respectively. Though total weight loss showed no significant difference, patients undergoing SG faced higher conversion rates due to inadequate weight […]
Author: STITCHES Newsletter
Metabolic and bariatric surgery reduces cardiovascular risks in obesity.
A comparative analysis of metabolic and bariatric surgery (MBS) versus glucagon-like peptide-1 receptor agonist (GLP-1 RA) therapy indicated that MBS significantly lowers the hazard of cardiovascular disease in patients with obesity. Specifically, MBS demonstrated a reduced risk for the primary composite outcome of cardiovascular disease (HR 0.54) and secondary outcomes including heart failure (HR 0.45), […]
Molecular Differences in Pancreatic Cancer Highlight Racial Disparities
Racial disparities in pancreatic cancer survival are linked to distinct immune microenvironments and genomic profiles. In a comprehensive analysis of 4,679 pancreatic adenocarcinoma samples, African American patients exhibited a higher frequency of TP53 mutations than European Americans. Additionally, gene expression profiling indicated significant immunologic differences between the two groups. These findings suggest that understanding these […]
Heterogeneity in trauma triage tool application identified
A hybrid systematic review examined 92 papers on trauma triage tools (TTTs), revealing significant variability in the application of prehospital characteristics across international studies. While higher-level categories such as physiological measurements and injury mechanisms were consistent, the specific thresholds and interpretations used varied widely. This inconsistency may lead to sub-optimal clinical decision-making and highlights the […]
Pelvic peritoneal reconstruction reduces postoperative complications in rectal cancer
A systematic review and meta-analysis of 16 cohort studies demonstrated that patients undergoing pelvic peritoneal reconstruction (PPC) during abdominoperineal resection for rectal cancer experienced significantly lower rates of postoperative complications. The PPC group showed reduced odds for intestinal obstruction (OR = 0.22), surgical site infections (OR = 0.36), and pelvic and abdominal cavity infections (OR […]
EUS-guided drainage proves effective for postoperative fluid collections
First-intention endoscopic ultrasound-guided drainage (EUS-pcd) using lumen-apposing metal stents (LAMS) demonstrated a technical success rate of 97.0% and a clinical success rate of 95.2% in managing postoperative collections (PCs) from various surgeries. The median size of collections was 7.6 cm, occurring about 19 days post-surgery. Only 9.1% experienced adverse events, with just one severe case […]
Minimally invasive endoscopic onlay repair shows low complication rates
A systematic review and meta-analysis of 12 studies involving 480 patients indicated that minimally invasive endoscopic onlay repair (endor) for diastasis recti and ventral hernia is a safe technique. The intraoperative complication and conversion rates were low at 1%, with a seroma rate of 25%. Postoperative complications included a 1% rate of surgical site infections […]
Continuous glucose monitoring may enhance surgical outcomes for diabetes patients
A multicentre, parallel-arm, randomised trial in China aims to assess whether continuous glucose monitoring (CGM) improves surgical outcomes for patients with diabetes or impaired glucose tolerance compared to conventional monitoring. The study targets a significant cohort of over 10,000 participants and measures the comprehensive complication index (CCI) within 30 postoperative days. By employing rigorous statistical […]
Epithelial type influences postoperative outcomes in IPMNs
A multicenter analysis of 556 patients with intraductal papillary mucinous neoplasms indicated that epithelial types significantly affect postoperative results. The pancreatobiliary type demonstrated a notably higher 10-year cumulative incidence of metachronous pancreatic ductal adenocarcinoma (22.7%) and high-risk lesions (37.2%) compared to gastric and intestinal types. Five-year disease-specific survival rates varied substantially, with 76.1% for the […]
Nomogram predicts risk of pulmonary infections in surgery patients
A novel nomogram developed by clinicians accurately predicts postoperative pulmonary infections (popis) in esophageal cancer patients. Evaluated across 910 patients, it identified six independent risk factors: age, anemia, neoadjuvant therapy, T stage, thoracic adhesions, and duration of surgery. The model demonstrated strong discrimination with areas under the curve (AUC) of 0.8095, 0.8039, and 0.7174 in […]