Preoperative C-reactive protein-to-albumin ratio (CAR) ≥ 0.049 was identified as an independent risk factor for anastomotic leakage (AL) in rectal cancer patients undergoing surgery with intraoperative indocyanine green fluorescence imaging (ICG-FI). CAR could serve as a criterion for early surgical intervention or consideration of interventions like diverting stoma creation, potentially lowering the incidence of AL […]
Author: STITCHES Newsletter
Aprepitant Effectively Prevents Post-bariatric Surgery Nausea and Vomiting
Aprepitant significantly reduces postoperative nausea and vomiting in patients undergoing metabolic bariatric surgery, improving recovery and patient satisfaction. Meta-analysis of six studies involving 929 patients showed a significant decrease in ponv incidence with aprepitant, particularly at 0, 6, and 12 hours postoperatively. Administering aprepitant within the first 24 hours post-surgery is recommended for optimal efficacy. […]
Perioperative Biobank Study: Examining High-Risk Surgical Complications
Postoperative complications in high-risk surgical populations increase mortality, disability, and costs. BIGPROMISE cohort profile discusses rationale and scope to investigate risk factors and outcomes related to postoperative complications. Over 3000 adult patients undergoing major surgery contribute data and biomarkers for analysis. With a focus on pathophysiological processes, the study aims to improve risk stratification for […]
Food Environment Impacts Gastrointestinal Cancer Outcomes
Patients in regions with poorer food environments exhibit higher odds of late-stage gastrointestinal cancer diagnosis and worse survival rates. These disparities are pronounced across various cancer types, highlighting the need for targeted interventions to mitigate socioeconomic and dietary influences on cancer outcomes. Journal Article by Fei-Zhang DJ, Schellenberg SJ (…) Pawlik TM et 2 al. […]
Thick mesopancreas predicts surgical outcomes in pancreaticoduodenectomy
Patients undergoing pancreaticoduodenectomy with a thick mesopancreas face significantly longer operative times, higher estimated blood loss, fewer resected lymph nodes, increased overall and major morbidities, and prolonged hospital stays. This study underscores the mesopancreas thickness as a critical predictor of surgical outcomes, surpassing the predictive value of body mass index. Tailoring surgical strategies based on […]
Comparable Postoperative Outcomes by IMG Surgeons
Postoperative outcomes among patients treated by international medical graduate (IMG) surgeons were comparable to those by United States medical graduate (USMG) surgeons. IMG surgeons had lower rates of adverse postoperative outcomes, such as 90-day readmission and index complications. They were also more likely to care for patients with multiple comorbidities and from vulnerable communities, showcasing […]
Postoperative Complications and Patient-Reported Outcomes
Postoperative complications were associated with significantly worse patient-reported outcomes, including lower physical and mental health scores, higher pain interference and fatigue, and lower physical function. A substantial number of patients reported outcomes below national benchmarks, emphasizing the need for improved post-surgical care to enhance patients’ quality of life. This study highlights the critical impact of […]
Complications Associated with 30-Day Mortality After General Surgery
Among general surgery patients, major bleeding, sepsis, and myocardial injury after non-cardiac surgery (MINS) were independently associated with 30-day mortality. These complications had the largest attributable fraction of post-operative deaths. Findings suggest the need for strategies, such as perioperative bleeding prophylaxis, to reduce mortality in this patient population. Journal Article by Park LJ, Borges FK […]
Key Risk Factors for Rectal Cancer Recurrence
Success in rectal cancer treatment depends on predicting recurrence risks. Swedish registry data on 9428 patients revealed major impacts on distant recurrence from factors like pt4a, pn2b, tumor deposit, lymph node yield, and tumor level. Pathologic stage and identified risk factors guided different recurrence risks across treatment groups. Recognizing key risk factors alongside stage allows […]
Impact of 3-Month Excessive Weight Loss on Post-Gastric Sleeve Outcomes
Early body-weight loss (< 37.7% EBWL) at 3 months post-laparoscopic sleeve gastrectomy predicts poorer long-term weight loss outcomes. High BMI, elevated neutrophil-to-lymphocyte ratio (≥ 2.36), and female sex are significant risk factors for suboptimal weight loss. These findings highlight the potential utility of targeted interventions such as adjuvant weight loss medications in at-risk patients. Journal […]