The study analyzed the implications of the geometric location (fundal end vs cystic ductal end) of gallbladder cancer on postoperative outcomes. Researchers compared the oncologic outcomes of 575 patients with gallbladder cancer and found that patients with cancer located on the cystic ductal end had significantly lower rates of recurrence-free survival and overall survival compared […]

Studies comparing organ-preserving pancreatectomy procedures have shown that central pancreatectomy (CP) leads to a lower incidence of new-onset or exacerbated diabetes compared to distal pancreatectomy (DP). However, CP is associated with increased morbidities such as pancreatic fistula. Spleen-preserving DP using the Kimura procedure reduces the risk of postoperative gastric varices and splenic infarction, but its […]

Distinct intra-tumoral cell neighborhoods were identified in pancreatic ductal adenocarcinoma (PDA), with variations in immune and tumor cell subsets based on neighboring cells. Tumors from long-term survivors had a higher presence of stromal-associated macrophages, while short-term survivors had more immune-excluded tumor cells. Chemotherapy-treated tumors showed lower quantities of tumor-associated T cells and macrophages, but higher […]

A multicenter study developed and validated the prealbumin-bilirubin (preALBI) score as an alternative to the widely used albumin-bilirubin (ALBI) score for predicting long-term survival after hepatectomy for hepatocellular carcinoma (HCC). The preALBI score, incorporating serum prealbumin and bilirubin levels, showed superior performance in predicting survival compared to the ALBI score and Child-Pugh grade. Leveraging the […]