Category: Endocrine Surgery

Higher recurrence rates for primary hyperparathyroidism found after less than subtotal parathyroidectomy in patients with multiple endocrine neoplasia type 1

Recurrence rates for primary hyperparathyroidism (PHPT) in patients with multiple endocrine neoplasia type 1 (MEN1) were assessed based on the type of surgery performed, and risk factors for recurrence were identified. The study found that recurrence was significantly higher after less than subtotal parathyroidectomy (LTSP) compared to subtotal parathyroidectomy (STP). The median time to recurrence […]

Enhanced Detection of the Recurrent Laryngeal Nerve Using Fluorescence Imaging during Thyroidectomy Procedures

Fluorescence imaging during thyroidectomy procedures significantly enhances the detection of the recurrent laryngeal nerve (RLN) with 100% sensitivity and specificity. All 81 RLNs observed were more clearly visualized under fluorescence compared to thyroid or background tissue. Fluorescence imaging also allowed for the visualization of all 30 RLNs and 45 nerve branches, whereas white light only […]

Practice Patterns and Factors Associated with Intraoperative Nerve Monitoring in Endocrine Surgery

Among 9,813 patients who underwent parathyroidectomy, intraoperative nerve monitoring was used in 49% of cases. There was a significant increase in parathyroidectomies with intraoperative nerve monitoring from 2014 to 2018, followed by a plateau. Vocal cord dysfunction after parathyroidectomy was not associated with intraoperative nerve monitoring. Surgeons who routinely used intraoperative nerve monitoring during thyroidectomy […]

Long-Term Impact of Genotype and Surgery in MEN1 Hyperparathyroidism

The study investigated the impact of genotype and surgical approach on long-term postoperative outcomes in patients with primary hyperparathyroidism and multiple endocrine neoplasia type 1 (MEN1). Findings showed that patients with protein-truncating germline pathogenic variants in specific exons of the MEN1 gene had aggressive pancreatic neuroendocrine tumors and earlier onset of primary hyperparathyroidism. The choice […]

Intraoperative Parathyroid Hormone Monitoring Predicts Successful Treatment of Parathyroid Carcinoma

A retrospective review of 796 patients undergoing parathyroidectomy with intraoperative parathyroid hormone (iPTH) monitoring for primary hyperparathyroidism identified 18 patients with parathyroid carcinoma. The study found that patients who achieved a >50% decrease in iPTH levels into the normal reference range had a higher rate of operative success compared to those with a >50% decrease […]

Systemwide Quality Improvement Increases Primary Care-Initiated Evaluation of Adrenal Incidentalomas

Following the implementation of a systemwide quality improvement (QI) program, researchers assessed the management of incidental adrenal masses (IAMS) in 437 patients from January 2018 to December 2019. The QI intervention included various strategies such as providing chart-based messages, emails to primary care providers (PCPs), standardized recommendations, and access to a multispecialty adrenal clinic. The […]

Gasless Single-Incision Endoscopic Surgery for Lateral Neck Dissection in Papillary Thyroid Cancer: Scarless Cervical Appearence and Good Efficacy

Gasless single-incision endoscopic surgery via subclavicular approach (ESSA) is a safe and effective procedure for lateral neck dissection in patients with papillary thyroid cancer. Results showed that ESSA had comparable lymph node yield to video-assisted endoscopic surgery (VAES) and open surgery (OP), while also resulting in lower swallowing impairment scores and higher cosmetic satisfaction rates. […]

Advantages of Retroperitoneal Laparoscopic Adrenalectomy for Small Tumors

A comparative study was conducted to compare the effectiveness and safety of transabdominal and retroperitoneal laparoscopic adrenalectomies. The study involved 472 patients, with laparoscopic transabdominal adrenalectomies (LTA) being the preferred approach for most surgeons. It was found that retroperitoneal adrenalectomies (RPA) had advantages in terms of surgery time, blood loss, post-op pain, and recovery for […]

Gasless TOETVA and Open Surgery have Comparable Effects on Oral Function and Psychological Well-being in Papillary Thyroid Cancer Patients

The study analyzed 212 papillary thyroid cancer patients who underwent either gasless transoral endoscopic thyroidectomy vestibular approach (TOETVA) or open surgery. The gasless TOETVA group exhibited higher oral health impact profile-14 scores in the first year after surgery compared to the open surgery group, but the difference disappeared after one year. State anxiety scores did […]

Central Lymph Nodes in Frozen Sections Predict Extended Lymph Node Resection Need in Papillary Thyroid Carcinoma

Central lymph node metastasis (CLNM) in frozen sections accurately predicted neck lateral lymph node metastasis (NLLNM) in patients with papillary thyroid carcinoma (PTC). Furthermore, risk factors for NLLNM metastasis were identified, including maximum metastatic diameter, total number, and ratio of metastatic lymph nodes (LNs). Based on these findings, patients with PTC with >5 CLNMs, 2-5 […]