Researchers scrutinized 3421 medullary thyroid cancer (MTC) cases to see if the 2009 American Thyroid Association (ATA) guidelines had a real impact. Post-2009, 72% of non-advanced MTC cases aligned with surgery guidelines, up from 67%. Discordant cases often featured females, older patients, and non-academic facilities. Most crucially, sticking to guidelines meant better survival odds. With […]
Category: Endocrine Surgery
Reducing Parathyroid Tissue Removal: Near-Infrared Autofluorescence in Thyroid Surgery
This study explored the impact of near-infrared autofluorescence imaging during thyroid surgery on the inadvertent removal of parathyroid tissue. Comparing patients who underwent total thyroidectomy with or without this imaging tool, the results showed a lower rate of accidental parathyroid tissue removal in the near-infrared autofluorescence group. The reduction was more significant when this technology […]
Thyroid Surgery After Radiofrequency Ablation: Safe and Effective
Researchers assessed the impact of radiofrequency ablation on subsequent thyroid surgery. They compared outcomes and complications between patients who had thyroidectomy after radiofrequency ablation and those without prior ablation. The study included 96 patients, with no significant differences in operative time or complications between the groups. Importantly, no permanent complications were reported. This study suggests […]
Radiofrequency Ablation May Benefit Younger Patients with Thyroid Microcarcinoma
Researchers examined the best approach for treating papillary thyroid microcarcinoma, offering choices like radiofrequency ablation, active surveillance, or surgery. Their mathematical model assessed the likelihood of cancer progression, the need for thyroid replacement therapy, and treatment complications. Radiofrequency ablation outperformed active surveillance in averting progression and the need for lifelong thyroid therapy. Yet, the cost […]
Social Determinants Impact Thyroid Cancer Outcomes
This study delves into the influence of social determinants of health on thyroid cancer patients. Researchers scrutinized data from over 142,000 cases and discovered that longer delays in treatment resulted in higher mortality rates. Moreover, patients facing adverse social determinants of health, such as low income, education, and lack of insurance, experienced delayed treatment. The […]
Thyroid Hormone Receptor Alpha: A Potential Game-Changer in Liver Fibrosis
This study explores the role of thyroid hormones (TH) and their receptor, TRα, in hepatic fibrogenesis, a key process in chronic liver disease. Researchers found that TRα plays a dominant role in hepatic stellate cells (HSC) and can modulate fibrogenic gene expression. TH, specifically T3, inhibited fibrogenic responses in HSC and reduced liver fibrogenesis in […]
EUS-Guided Radiofrequency Ablation: A Safe and Effective Alternative for Left Adrenal Tumors
Researchers conducted a study at Asan Medical Center to assess the feasibility, effectiveness, and safety of EUS-guided radiofrequency ablation (EUS-RFA) for treating left adrenal tumors. The results were promising, with a 100% technical success rate in performing EUS-RFA. Most patients (73%) achieved a complete response after a median of 2 EUS-RFA sessions. Importantly, no moderate […]
Hemithyroidectomy Found Effective for Noninvasive Medullary Thyroid Tumors
In patients with nonmetastatic medullary thyroid cancer, researchers examined the use of hemithyroidectomy, a less extensive surgery, instead of total thyroidectomy. They identified two types of tumors, desmoplasia-negative and desmoplasia-positive, based on markers in the tumor tissue. The results showed that patients with desmoplasia-negative tumors who had hemithyroidectomy achieved a biochemical cure without compromising their […]
Diameter Trumps Volume in Monitoring High-Risk Thyroid Nodule Growth
In the evaluation of disease progression within high-risk thyroid nodules during active surveillance, researchers compared the effectiveness of tracking tumor diameter versus volume. Among 468 patients with a total of 569 high-risk thyroid nodules, only 2.5% showed a significant diameter increase of ≥3 mm, while volume fluctuations of 50% and 100% were noted in 32.5% […]
TOETVA: Aesthetic Thyroid Surgery Learning Curve and Castle Tumor Case
The transoral endoscopic thyroidectomy vestibular approach (TOETVA) offers a cosmetic edge over traditional thyroid surgery. Researchers assessed TOETVA’s learning curve and its effectiveness in treating carcinoma showing thymus-like differentiation (CASTLE) tumors. The study found longer operation times in TOETVA, but it excelled in skin numbness and cosmetic outcomes. The learning curve analysis revealed that a […]
