Investigating primary hyperparathyroidism referrals, a study analyzed 1,100 patients and found that sex concordance (matching patient and practitioner sexes) correlated with increased specialist evaluations. Patients with concordant primary care practitioners had 32% higher odds of endocrinologist evaluation, and those with concordant endocrinologists had a 48% higher rate of surgeon evaluation. Stratified analysis revealed that sex […]

In the realm of thyroid cancer, where iodine treatment falls short for some, researchers explored a new ally. The thyroid-stimulating hormone receptor (TSHR) took the spotlight, showing up in 62% of patients’ thyroid tissues. With a specially crafted radiolabeled compound, researchers witnessed TSHR’s potential for imaging differentiated thyroid cancer. This breakthrough hints at a fresh […]

In treating differentiated thyroid cancer, various surgical methods were compared for integrity, safety, efficacy, and patient experience. The study, including 7042 patients, found that the endoscopic transoral approach (EOA) excelled in maintaining surgical integrity and minimizing pain. Robotic bilateral axillo-breast approach (RBABA) protected parathyroid glands and the recurrent laryngeal nerve but had the longest operative […]

A groundbreaking study tracked 1613 patients with low-risk papillary thyroid carcinoma (PTC) who underwent radiofrequency ablation (RFA) for an impressive 58.5 months. Results unveiled a remarkable 4.3% local tumor progression rate, with a 95.7% disease-free survival at 8 years. Subcapsular tumor location and multifocality were risk factors, emphasizing RFA’s efficacy. Unifocal, smaller tumors correlated with […]

Researchers scrutinized 3421 medullary thyroid cancer (MTC) cases to see if the 2009 American Thyroid Association (ATA) guidelines had a real impact. Post-2009, 72% of non-advanced MTC cases aligned with surgery guidelines, up from 67%. Discordant cases often featured females, older patients, and non-academic facilities. Most crucially, sticking to guidelines meant better survival odds. With […]

This study explored the impact of near-infrared autofluorescence imaging during thyroid surgery on the inadvertent removal of parathyroid tissue. Comparing patients who underwent total thyroidectomy with or without this imaging tool, the results showed a lower rate of accidental parathyroid tissue removal in the near-infrared autofluorescence group. The reduction was more significant when this technology […]

Researchers assessed the impact of radiofrequency ablation on subsequent thyroid surgery. They compared outcomes and complications between patients who had thyroidectomy after radiofrequency ablation and those without prior ablation. The study included 96 patients, with no significant differences in operative time or complications between the groups. Importantly, no permanent complications were reported. This study suggests […]

Researchers examined the best approach for treating papillary thyroid microcarcinoma, offering choices like radiofrequency ablation, active surveillance, or surgery. Their mathematical model assessed the likelihood of cancer progression, the need for thyroid replacement therapy, and treatment complications. Radiofrequency ablation outperformed active surveillance in averting progression and the need for lifelong thyroid therapy. Yet, the cost […]

This study delves into the influence of social determinants of health on thyroid cancer patients. Researchers scrutinized data from over 142,000 cases and discovered that longer delays in treatment resulted in higher mortality rates. Moreover, patients facing adverse social determinants of health, such as low income, education, and lack of insurance, experienced delayed treatment. The […]

This study explores the role of thyroid hormones (TH) and their receptor, TRα, in hepatic fibrogenesis, a key process in chronic liver disease. Researchers found that TRα plays a dominant role in hepatic stellate cells (HSC) and can modulate fibrogenic gene expression. TH, specifically T3, inhibited fibrogenic responses in HSC and reduced liver fibrogenesis in […]