A novel deep learning model significantly enhances the preoperative diagnosis of follicular-patterned thyroid neoplasms (FNs) using routine ultrasound images. In extensive multicenter validation, the model achieved an impressive AUC of 0.937 for internal and 0.853 for external cohorts. Moreover, it demonstrated high accuracy (90.9% and 82.8%) and sensitivity (93.9% and 84.5%), streamlining clinical decision-making and […]

A seven-gene prognostic model derived from the ATF/CREB family effectively stratifies adrenocortical carcinoma (ACC) patients into high- and low-risk groups based on overall survival. This model not only serves as an independent prognostic factor across various clinical settings but also reveals unique immune characteristics linked to high-risk patients, including reduced CD8+ T cell presence and […]

Researchers introduced a novel liver retraction approach for laparoscopic right adrenalectomy using basic local tools, enhancing feasibility in resource-limited settings. This technique, featuring a unique port configuration and ergonomic support, was designed to prevent liver injury while ensuring optimal surgical exposure. Its simplicity and cost-effectiveness demonstrate potential for broad adoption in developing countries, addressing challenges […]

A systematic review of 23 studies involving 2,470 adults with primary hyperparathyroidism demonstrated the feasibility of minimally invasive parathyroidectomy under local anesthesia. Operative times averaged 43.86 minutes with a 95-97% success rate. Patients experienced a mean hospitalization of just 16.83 hours and relatively few complications. Preoperative and postoperative parathyroid hormone and calcium levels showed significant […]

A nationwide survey revealed that 67.14% of Italian endocrine surgeons now routinely employ intraoperative nerve monitoring (IONM) during thyroid and parathyroid surgeries. This marks a significant increase since 2014, indicating improved surgical safety and reduced complication rates. Despite growing acceptance, challenges such as the variability in monitoring strategies and the occurrence of false results remain. […]

Incentive nursing care (ICN) alongside routine nursing care (RNC) significantly enhances the management of depression and anxiety in thyroid cancer patients undergoing surgery. A meta-analysis of 12 trials with 999 participants revealed notable improvements in self-reported depression and anxiety levels, as well as overall quality of life measures. Results indicated that ICN plus RNC outperformed […]

A meta-analysis of 43 randomized controlled trials involving over 10,000 patients indicates the sutureless focus harmonic scalpel (UAS) is superior to the conventional clamp-and-tie technique in total thyroidectomy. Notably, the incidence of transient recurrent laryngeal nerve palsy was significantly lower with UAS (3.99% vs. 5.23%). Similarly, transient hypocalcemia occurred less frequently in UAS patients (11.3% […]

A comparative analysis of single-port techniques for adrenalectomies revealed that single-port single-channel laparoscopic surgery offers significant benefits for tumors up to 4 cm, including reduced hospital stay and pain. For tumors exceeding 4 cm, single-port multi-channel approaches facilitate shorter hospital stays and fewer additional punctures. All 218 adrenalectomies were successfully performed without conversion to open […]

A meta-analysis of 43 randomized controlled trials involving 10,361 patients reveals that the sutureless focus harmonic scalpel significantly lowers the risk of complications during thyroidectomy. The transient recurrent laryngeal nerve injury was reduced to 3.99% with the scalpel compared to 5.23% with the clamp-and-tie technique. Additionally, transient hypocalcemia rates were lower (11.3% vs. 15.4%). These […]